Publications

Brinda AK, Doyle AM, Blumenfeld M, Krieg J, Alisch JR, Spencer C, Lecy E, Wilmerding LK, DeNicola A, Johnson LA, Vitek JL, Johnson MD. Longitudinal analysis of local field potentials recorded from directional deep brain stimulation lead implants in the subthalamic nucleus. J Neural Eng. 2021 Apr 27; PMID: 33906174

Johnson LA, Aman JE, Yu Y, Sanabria DE, Wang J, Hill M, Dharnipragada R, Patriat R, Fiecas M, Li L, Schrock LE, Cooper SE, Johnson MD, Park MC, Harel N, Vitek JL. High-Frequency Oscillations in the Pallidum: A Pathophysiological Biomarker in Parkinson’s Disease? Movement Disorders [Internet]. [cited 2021 Apr 14];n/a(n/a). Available from: http://movementdisorders.onlinelibrary.wiley.com/doi/abs/10.1002/mds.28566

Schrock LE, Patriat R, Goftari M, Kim J, Johnson MD, Harel N, Vitek JL. 7T MRI and Computational Modeling Supports a Critical Role of Lead Location in Determining Outcomes for Deep Brain Stimulation: A Case Report. Front Hum Neurosci. 2021;15:631778. PMCID: PMC7928296

Yu Y, Sanabria DE, Wang J, Hendrix CM, Zhang J, Nebeck SD, Amundson AM, Busby ZB, Bauer DL, Johnson MD, Johnson LA, Vitek JL. Parkinsonism alters beta burst dynamics across the basal ganglia-motor cortical network. J Neurosci [Internet]. Society for Neuroscience; 2021 Jan 22 [cited 2021 Jan 25]; Available from: http://www.jneurosci.org/content/early/2021/01/22/JNEUROSCI.1591-20.2021 PMID: 33483430

Sanabria DE, Johnson LA, Yu Y, Busby Z, Nebeck S, Zhang J, Harel N, Johnson MD, Molnar GF, Vitek JL. Real-time suppression and amplification of frequency-specific neural activity using stimulation evoked oscillations. Brain Stimulation: Basic, Translational, and Clinical Research in Neuromodulation. Elsevier; 2020 Nov 1;13(6):1732–1742. PMID: 33035727

Johnson L, Alekseichuk I, Krieg J, Doyle A, Yu Y, Vitek J, Johnson M, Opitz A. Dose-dependent effects of transcranial alternating current stimulation on spike timing in awake nonhuman primates. Science Advances. American Association for the Advancement of Science; 2020 Sep 1;6(36):eaaz2747. PMID: 32917605

Lungu C, Ozelius L, Standaert D, Hallett M, Sieber B-A, Swanson-Fisher C, Berman BD, Calakos N, Moore JC, Perlmutter JS, Pirio Richardson SE, Saunders-Pullman R, Scheinfeldt L, Sharma N, Sillitoe R, Simonyan K, Starr PA, Taylor A, Vitek J, participants and organizers of the NINDS Workshop on Research Priorities in Dystonia. Defining research priorities in dystonia. Neurology. 2020 Mar 24;94(12):526–537. PMCID: PMC7274927

Aman JE and Johnson LA, Sanabria DE, Wang J, Patriat R, Hill M, Marshall E, MacKinnon CD, Cooper SE, Schrock LE, Park MC, Harel N, Vitek JL. Directional deep brain stimulation leads reveal spatially distinct oscillatory activity in the globus pallidus internus of Parkinson’s disease patients. Neurobiology of Disease. 2020 Jun 1;139:104819.

Johnson LA and Wang J, Nebeck SD, Zhang J, Johnson MD, Vitek JL. Direct Activation of Primary Motor Cortex during Subthalamic But Not Pallidal Deep Brain Stimulation. J Neurosci. 2020 Mar 4;40(10):2166–2177. PMID: 32019827

Vitek JL, Johnson LA. Understanding Parkinson’s disease and deep brain stimulation: Role of monkey models. Proc Natl Acad Sci U S A. 2019 Dec 26;116(52):26259–26265. PMCID: PMC6936402

Hendrix CM, Campbell BA, Tittle BJ, Johnson LA, Baker KB, Johnson MD, Molnar GF, Vitek JL. Predictive encoding of motor behavior in the supplementary motor area is disrupted in Parkinsonism. J Neurophysiol. 2018 Jun 6; PMID: 29873615Z: Link 

Escobar Sanabria D and Johnson LA, Nebeck SD, Zhang J, Johnson MD, Baker KB, Molnar GF, Vitek JL. Parkinsonism and Vigilance: Alteration in neural oscillatory activity and phase-amplitude coupling in the basal ganglia and motor cortex. Journal of Neurophysiology 2017 Nov 1;118(5):2654-2669. doi: 10.1152/jn.00388.2017. PMID: 28835526: Link to Podcast

Wang J, Johnson LA, Jensen AL, Baker KB, Molnar GF, Johnson MD,  Vitek JL, Network wide oscillations in the parkinsonian state: Alterations in neuronal activities occur in the premotor cortex in parkinsonian non-human primates. Journal of Neurophysiology, 2017, 117(6), 2242–2249

Muralidharan A, Zhang J, Ghosh D, Johnson M, Baker KB, Vitek, JL. Modulation of Neuronal Activity in the Motor Thalamus during GPi-DBS in the MPTP Model of Parkinson's Disease. Brain Stimul. 2017 Jan - Feb;10(1):126-138  DOI: http://dx.doi.org/10.1016/j.brs.2016.10.005

Hopfner F, Haubenberger D, Galpern WR, Gwinn K, Van't Veer A, White S, Bhatia K, Adler CH, Eidelberg D, Ondo W, Stebbins GT, Tanner CM, Helmich RC, Lenz FA, Sillitoe RV, Vaillancourt D, Vitek JL, Louis ED, Shill HA, Frosch MP, Foroud T, Kuhlenbäumer G, Singleton A, Testa CM, Hallett M, Elble R, Deuschl G. Knowledge gaps and research recommendations for essential tremor. Parkinsonism Relat Disord. 2016 Dec;33:27-35. doi: 10.1016/j.parkreldis.2016.10.002

Wang J, Nebeck S, Muralidharan A, Johnson MD, Vitek JL, Baker KB. Coordinated Reset Deep Brain Stimulation of Subthalamic Nucleus Produces Long-Lasting, Dose-Dependent Motor Improvements in the 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine Non-Human Primate Model of Parkinsonism. Brain Stimulation. 2016 Jul 1;9(4):609–617.

Johnson LA, Nebeck SD, Muralidharan A, Johnson MD, Baker KB, Vitek JL, 2016, Closed-loop deep brain stimulation effects on parkinsonian motor symptoms in a non-human primate -- is beta enough? Brain Stimulation. DOI: 10.1016/j.brs.2016.06.051

Muralidharan A, Jensen AL, Connolly A, Hendrix CM, Johnson MD, et al. Physiological changes in the pallidum in a progressive model of Parkinson's disease: Are oscillations enough? Experimental neurology. 2016; 279:187-196. PubMed PMID: 26946223

Dorval AD, Muralidharan A, Jensen AL, Baker KB, Vitek JL. Information in pallidal neurons increases with parkinsonian severity. Parkinsonism & related disorders. 2015; 21(11):1355-61. NIHMSID: NIHMS727590 PubMed PMID: 26433544 PMCID: PMC4631644

Connolly AT, Jensen AL, Baker KB, Vitek JL, Johnson MD. Classification of pallidal oscillations with increasing parkinsonian severity. Journal of neurophysiology. 2015; 114(1):209-18. PubMed PMID: 25878156 PMCID: PMC4507953

Connolly AT, Jensen AL, Bello EM, Netoff TI, Baker KB, et al. Modulations in oscillatory frequency and coupling in globus pallidus with increasing parkinsonian severity. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2015; 35(15):6231-40. PubMed PMID: 25878293 PMCID: PMC4397612

Johnson LA, Xu W, Baker KB, Zhang J, Vitek JL. Modulation of motor cortex neuronal activity and motor behavior during subthalamic nucleus stimulation in the normal primate. Journal of neurophysiology. 2015; 113(7):2549-54. PubMed PMID: 25673744 PMCID: PMC4416594

Pulliam CL, Heldman DA, Orcutt TH, Mera TO, Giuffrida JP, et al. Motion sensor strategies for automated optimization of deep brain stimulation in Parkinson's disease.  Parkinsonism & related disorders. 2015; 21(4):378-82. PubMed PMID: 25703990 PMCID: PMC4372473

Zitella LM, Xiao Y, Teplitzky BA, Kastl DJ, Duchin Y, et al. In Vivo 7T MRI of the Non-Human Primate Brainstem. PloS one. 2015; 10(5):e0127049. PubMed PMID: 25965401 PMCID: PMC4428864

Volkmann J, Mueller J, Deuschl G, Kühn AA, Krauss JK, et al. Pallidal neurostimulation in patients with medication-refractory cervical dystonia: a randomised, sham-controlled trial. The Lancet. Neurology. 2014; 13(9):875-84. PubMed PMID: 25127231

Kobayashi K, Liu CC, Jensen AL, Vitek JL, Mari Z, et al. Thalamic post-inhibitory bursting occurs in patients with organic dystonia more often than controls. Brain research. 2013; 1541:81-91. NIHMSID: NIHMS535384 PubMed PMID: 24125808 PMCID: PMC388980

 

Miocinovic S, Somayajula S, Chitnis S, Vitek JL. History, applications, and mechanisms of deep brain stimulation. JAMA neurology. 2013; 70(2):163-71. PubMed PMID: 23407652

Cooper SE, McIntyre CC, Fernandez HH, Vitek JL. Association of deep brain stimulation washout effects with Parkinson disease duration. JAMA neurology. 2013; 70(1):95-9. PubMed PMID: 23070397

Agnesi F, Johnson MD, Vitek JL. Deep brain stimulation: how does it work? Handbook of clinical neurology. 2013; 116:39-54. PubMed PMID: 24112883

Agnesi F, Connolly AT, Baker KB, Vitek JL, Johnson MD. Deep brain stimulation imposes complex informational lesions. PloS one. 2013; 8(8):e74462. PubMed PMID: 23991221 PMCID: PMC3753277

Hack N, Jicha GA, Abell A, Dean D, Vitek JL, et al. Substantia nigra depigmentation and exposure to encephalitis lethargica. Annals of neurology. 2012; 72(6):912-7. PubMed PMID: 23280841 PMCID: PMC3660013

Hendrix CM, Vitek JL. Toward a network model of dystonia. Annals of the New York Academy of Sciences. 2012; 1265:46-55. PubMed PMID: 22823747

Johnson MD, Zhang J, Ghosh D, McIntyre CC, Vitek JL. Neural targets for relieving parkinsonian rigidity and bradykinesia with pallidal deep brain stimulation. Journal of neurophysiology. 2012; 108(2):567-77. PubMed PMID: 22514292 PMCID: PMC3404794

Vitek JL. Long-term benefit from deep brain stimulation of the subthalamic nucleus: is it for everyone? Alzheimer's research & therapy. 2012; 4(3):13. PubMed PMID: 22574875 PMCID: PMC3506928

Okun MS, Gallo BV, Mandybur G, Jagid J, Foote KD, et al. Subthalamic deep brain stimulation with a constant-current device in Parkinson's disease: an open-label randomised controlled trial. The Lancet. Neurology. 2012; 11(2):140-9. PubMed PMID: 22239915

Vitek JL, Zhang J, Hashimoto T, Russo GS, Baker KB. External pallidal stimulation improves parkinsonian motor signs and modulates neuronal activity throughout the basal ganglia thalamic network. Experimental neurology. 2012; 233(1):581-6. NIHMSID: NIHMS329542 PubMed PMID: 22001773 PMCID: PMC3536483