News & Updates

NMRC lab members present research at Society for Neuroscience 2017

Multiple NMRC members presented posters at the Society for Neuroscience Annual meeting held in Washington D.C. November 2017

Tittle et al.

 

 

 

 

Aman et al.

 

 

 

 

Tittle et al.

 

 

 

 

Yu et al.

 

 

 

 

Publish Date: 
Thursday, November 30, 2017 - 1:45pm

Publication by David Escobar and Luke Johnson featured in Journal of Neurophysiology podcast

Click here for the podcast link

Oscillatory neural activity in different frequency bands and phase-amplitude coupling (PAC) are hypothesized to be biomarkers of Parkinson’s disease (PD). Might these activity features help explain PD motor dysfunction, and serve as viable targets for closed-loop deep brain stimulation (DBS)? In this podcast, Editor-in-Chief Bill Yates (University of Pittsburgh) talks with David Escobar Sanabria (Department of Neurology, University of Minnesota) and Luke Johnson (Department of Neurology, University of Minnesota) about a recent study which explored these questions. Their findings helped to characterize these biomarkers across various vigilance states, and to build a foundation for future therapeutic techniques.

Parkinsonism and vigilance: alteration in neural oscillatory activity and phase-amplitude coupling in the basal ganglia and motor cortex
David Escobar Sanabria, Luke A. Johnson, Shane D. Nebeck, Jianyu Zhang, Matthew D. Johnson, Kenneth B. Baker, Gregory F. Molnar, Jerrold L. Vitek
Journal of Neurophysiology, published online November 3, 2017. DOI: 10.1152/jn.00388.2017.

Publish Date: 
Monday, November 20, 2017 - 2:15pm

Dr. Joshua Aman Speaks at Dystonia Walk

Dr. Joshua Aman spoke at the 2nd  annual Twin Cities Dystonia Medical Research Foundation (DMRF) Zoo Walk this weekend invited by the local chairs of the event and national DMRF Director of Development, Debbie Durrer. The Twin Cities Zoo Walk had over 300 registrants for its second event and raised funds for research towards a cure for Dystonia as well as helped bring awareness and education about Dystonia.

Joshua Aman speaks at Twin Cities Dystonia Zoo Walk

Dr. Joshua Aman speaks about why he researches Dystonia
 

The Twin Cities is one of 10 locations across the U.S. that hosted a Zoo Walk in 2017. More than 5000 individuals attended Dystonia Zoo Walks around the country in 2016. This is the second year that the Twin Cities held this fundraising event with the opportunity to generate public awareness of dystonia.

Saint Paul Mayor, Chris Coleman spoke to the crowd about the need for awareness and research. Billy McLaughlin formed a large team in support, spoke and introduced the Mayor. Debbie Durrer, Director of Development at DMRF ended her statement with "We won't rest until there is a cure."

Joshua Aman signing a TC Dystonia walker's shirt

Dr. Joshua Aman signs the t-shirt of a TC Dystonia Zoo Walk participant

Monies raised from DMRF fundraising events such as the Twin Cities Dystonia Zoo Walk go to funding research projects, advocacy, education and awareness, clinical fellowships,  and support groups.

TC Dystonia Zoo Walk group photo 2017

To learn more about Dystonia, please visit the Dystonia Medical Research Foundation

To find a movement disorder specialist at the University of Minnesota, Please visit M Health Neurology 
 

Publish Date: 
Wednesday, June 21, 2017 - 10:15am

Dr. Jerrold Vitek Speaks about DBS at Dystonia Educational Symposium

Dr. Jerrold Vitek was a guest speaker at the Dystonia Educational Symposium on April 29, 2017 in Saint Paul. The Symposium was an outreach event sponsored by the Dystonia Medical Research Foundation

Guest Speakers included Dr. Vitek, Dr. Lauren Schrock also of the Department of Neurology, and Dr. Jan Teller, Chief Scientific Officer of DMRF.

Topics included Deep Brain Stimulation (Vitek), Current Treatments (Schrock), and Research Updates (Teller). 

Jerry Vitek at Dystonia Educational Symposium

 

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Publish Date: 
Thursday, May 4, 2017 - 2:00pm

NMRC and Udall well represented at 5th annual Minnesota Neuromodulation Symposium

The Neuromodulation Research Center (NMRC) and University of Minnesota Udall Center of Excellence for Parkinson’s Disease Research were well represented at the 5th Annual Minnesota Neuromodulation Symposium.

Dr. Jerrold Vitek, Chair of the Department of Neurology, Director of the Neuromodulation Research Center, and Center Director of the University of Minnesota Udall Center of Excellence for Parkinson’s Disease Research, gave the first Plenary Talk which received high regards being mentioned throughout most of the first day of the symposium. Dr. Vitek was also part of a panel discussion regarding the opportunities and challenges in neuromodulation that concluded the seminar portion of day one.

Jerry Vitek gives plenary talk at Neuromodulation Symposium

 

Jerry Vitek gives plenary talk at Neuromodulation Symposium

 

Dr. Luke Johnson, of the Neuromodulation Research Center, was selected to present a highlight talk on his poster entitled “Subthalamic nucleus deep brain stimulation alters kinesthetic information processing in primary motor cortex.”  Over 100 posters were represented at the symposium, representing 58 different institutions, 24 non-profit organizations, 16 corporations and 16 countries;  of those, only 10 were invited to give highlight talks during the scientific program. These highlight talks allowed the selected speakers to provide a brief overview of their research to attract attendees to their posters.

Both NMRC and the Udall Center had posters represented in the poster session.

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Publish Date: 
Friday, April 14, 2017 - 1:15pm

Dr. Jerry Vitek shared his MNDrive supported research successes with the MN House Committee

Dr. Jerry Vitek shared his MNDrive supported research successes with the MN House Committee on March 1, 2017. Dr. Vitek gave testimony to the Senate Committee along with President Kaler, Dean Brooks Jackson, Dr. Mac Baird and Dr. Lauren Williams to request funding to expand MnDrive to launch a statewide clinical cancer trial network to enhance provider knowledge, increase patient access, improve treatments and survival rates. 

Jerry Vitek presents to senate

Jerry Vitek and Kaler present to Senate

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Publish Date: 
Thursday, March 2, 2017 - 12:45pm

Dr. Jerry Vitek talks Parkinson's Research Advancements

Neuromodulation Research Center Director and chair of the Department of Neurology, Dr. Jerry Vitek, visited Mankato to discuss DBS in an outreach effort. Read the full story in the Mankato Press  Researcher talks Parkinson’s treatment advances

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Publish Date: 
Wednesday, December 21, 2016 - 1:15pm

NMRC Members at SFN 2016

Multiple NMRC members presented posters at the Society for Neuroscience Annual meeting, held from November 12-16, 2016 in San Diego, CA.

Posters

415.02 Effect of parkinsonism and deep brain stimulation on neural oscillations and phase-amplitude coupling within the motor cortex, subthalamic nucleus and globus pallidus.
*D. ESCOBAR SANABRIA1, L. A. JOHNSON1, J. ZHANG1, S. NEBECK1, M. D. JOHNSON2, G. F. MOLNAR1, K. B. BAKER1, J. L. VITEK1
1
Neurol., 2Biomed. Engin., Univ. of Minnesota, Minneapolis, MN

Luke Johnson explaining poster at SFN 2016

David Escobar with poster at SFN 2016

 

415.06. Evolution in the modulation of passive responses in primary motor cortex during prolonged STN DBS in the parkinsonian
*J. WANG1, S. NEBECK1, L. A. JOHNSON1, J. ZHANG1, M. D. JOHNSON2, K. B. BAKER1, G. F. MOLNAR1, J. L. VITEK1
1
Neurol., 2Biomed. Engin., Univ. of Minnesota, Minneapolis, MN

Jing Wang poster at SFN 2016

 

415.05. Low frequency modulations in the Supplementary Motor Area (SMA) and motor cortex (MC) in the MPTP model of Parkinson’s disease.
*Y. ADIBI1, C. HENDRIX2, B. CAMPBELL2, K. BAKER2, J. L. VITEK2
2
Neurol., 1Univ. of Minnesota, Minneapolis, MN

 

415.03. Neuro-pathophysiology of SMA-M1 single unit activity during visually guided reach in the progressive MPTP  model of Parkinson’s disease
*B. CAMPBELL1, C. M. HENDRIX1, B. J. TITTLE1, Y. ADIBI1, Z. M. WEINSTOCK2, G. F. MOLNAR1, M. D. JOHNSON3, K. B. BAKER1, J. L. VITEK1
1
Neurol., 2Col. of Biol. Sci., 3Biomed. Engin., Univ. of Minnesota, Minneapolis, MN

Brett Campbell poster SFN 2016

 

415.07. Effect of levodopa on neuronal activity in primary motor cortex in the MPTP  model of Parkinson’s disease
S. D. NEBECK1, *L. A. JOHNSON1, J. ZHANG1, D. ESCOBAR1, M. D. JOHNSON2, G. MOLNAR1, K. B. BAKER1, J. L. VITEK1
1
Neurol., Univ. of Minnesota Dept. of Neurol., Minneapolis, MN; 2Univ. of Minnesota Dept. of Biomed. Engin., Minneapolis, MN​​​​​​​

Shane Nebeck Poster SNF 2016

 

 


 

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Publish Date: 
Wednesday, December 21, 2016 - 11:30am

NMRC at the State Fair

NMRC members were at the Minnsota State Fair to inform the public about deep brain stimulation (DBS) therapy for movement disorders and highlight the clinical DBS program and translational neuromodulation research being done at the University of Minnesota.

Neuromodulation booth at the Minnesota State Fair
 

 

 

 

 

 

 

 

 

Our group created a demo to educate people about DBS, with an example DBS device, a model brain, and a user interface that enabled visitors to interact with the demo and change DBS settings to "treat" various movement disorders. 

 

Jing Wang at the Neuromodulation booth Minnesota State Fair

We also represented MnDRIVE, which is an ongoing partnership between the University and the state of Minnesota that drives high-impact research and discovery in the field of neuromodulation.

Luke Johnson at the Neuromodulation booth at Minnesota State Fair

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Publish Date: 
Tuesday, September 13, 2016 - 9:30am

Luke Johnson Published

Luke Johnson and colleagues have a paper currently in press in Brain Stimulation. The article "Closed-loop deep brain stimulation effects on parkinsonian motor symptoms-- is beta enough?" was published 22 June 2016  with DOI: 10.1016/j.brs.2016.06.051

 

 

 

Publish Date: 
Monday, July 11, 2016 - 10:00am

Dr. Jerrold Vitek speaks at Dystonia Walk

Dr. Jerry Vitek spoke at the first annual Twin Cities Dystonia Medical Research Foundation (DMRF) Zoo Walk this weekend invited by the local chapter. The Twin Cities Zoo Walk had over 200 registrants for its first event and raised funds for research towards a cure for Dystonia as well as helped bring awareness and education about Dystonia.

Jerry vitek speaks at dystonia research foundation walk

 

The Twin Cities is one of 12 locations across the U.S. that hosted a Zoo Walk in 2016. Last year, Zoo Walks in 8 cities drew over 4,000 participants. This is the first year that the Twin Cities joined with the opportunity to generate public awareness of dystonia. The walk was featured on local WCCO and Fox9 and Governor Dayton declared June 11, 2016 to be Dystonia Awareness Day in the State of Minnesota.

Jerry Vitek and Sarah DuCloux-Potter at Dystonia Research Foundation Walk

To learn more about Dystonia, please visit the Dystonia Medical Research Foundation

To find a movement disorder specialist at the University of Minnesota, Please visit M Health Neurology or the Department of Neurology Physicians

Publish Date: 
Monday, June 13, 2016 - 9:15am

NMRC participates in Moving Day® Twin Cities

Members from the Neuromodulation Research Center along with many faculty and staff from the Department of Neurology participated in Moving Day® Twin Cities.

Moving Day Twin Cities Parkinson's photo

Moving Day® is the National Parkinson Foundation’s annual fundraising walk event. It is a fun and inspiring fundraising event that unites families, friends and communities both large and small in the fight against Parkinson’s disease. This celebration of movement will feature a family friendly walk course, a kids area, a caregivers relaxation tent and a special Movement Pavilion featuring yoga, dance, Tai Chi, Pilates, etc. all proven to help manage the symptoms of PD.

Moving Day Group Photo Parkinson's University of Minnesota Neurology

Team members of "Save The Neurons" from the University of Minnesota Department of Neurology, MNDrive, Department of Neurosurgery and Neuromodulation Research Center volunteered at the U of MN table, raised money and walked together on the course in what turned out to be a beautiful day. 

Parkinson's Walk Neuromodulation Research Members participate

Neuromodulation Research Center Members Moving Day

Publish Date: 
Sunday, May 8, 2016 - 11:00am

Luke Johnson receives poster award

Luke Johnson received a 2nd place poster award at the Minnesota Neuromodulation Symposium. 90 Posters were selected to be displayed at the symposium. Judges chose one 1st place, two 2nd place, and three 3rd place winners based on their originality, significance, and reliability of presented work.

Congratulations Luke on this prestigious award!

Publish Date: 
Wednesday, April 20, 2016 - 3:45pm

NMRC well represented at the Minnesota Neuromodulation Symposium

Bin He Presents Neuromodulation Research Center Slide Minnesota Neuromodulation Symposium

 

Members of the Neuromodulation Research Center spent two days at the Minnesota Neuromodulation Symposium networking with leaders in this exciting field, attending presentations, and presenting posters.

Luke Johnson was selected to give a highlight talk and gave an overview of his research to the symposium to attract viewers to his poster.

 

Luke Johnson Featured Talk Closed-Loop DBS Parkinson's

 

Five Posters were presented by members of the Neuromodulation Lab:

Closed-Loop Deep Brain Stimulation Effects on Parkinsonian Motor Symptoms -- Is Beta Enough? Luke A. Johnson, Shane D. Nebeck, Abirami Muralidharan, Matthew D. Johnson, Kenneth B. Baker, Greg Molnar, Jerrold L. Vitek 

Luke Johnson Poster Closed-Loop DBS

 

Characterization of Cortical SMA-M1 Neurophysiological Activity in the MPTP  Model of Parkinson’s Disease During a Goal Directed Reach Task. Brett A. Campbell, Claudia M. Hendrix, Zachary Weinstock, Yasaman Adibi, Kenneth Baker, Jerrold Vitek

Brett Campbell Claudia Hendrix Poster Cortical SMA-M1 

Low frequency Desynchronization in the Supplementary Motor Area (SMA) of Healthy and Parkinsonian ... Yasaman Adibi, Claudia Hendrix, Brett Campbell, Kenneth Baker, Jerrold L. Vitek 

Yasamin Adibi Poster motor area SMA parkinsonian

 

Phase-Amplitude Coupling in the STN and its Change Following Therapeutic STN DBS in the MPTP Model of Parkinson’s Disease.  Jing Wang, Shane Nebeck, Luke A. Johnson, Jianyu Zhang, Matthew D. Johnson, Kenneth B. Baker, Jerrold L. Vitek

Jing Wang Poster Parkinson's ​

Effect of Parkinsonism and Deep Brain Stimulation on Phase-Amplitude Correlations in  Globus Pallidus and Motor Cortex. David Escobar, Luke Johnson, Shane Neback, Matthew Johnson, Kenneth Baker, Gregory F. Molnar, Jerrold L. Vitek

David Escobar Poster

 

Gregory Molnar had a showing also with a poster from his prior research with Medical Device Innovation Consortium (MDIC).

Accelerating Patient Access to Neuromodulation Therapies: A Practical Tool to Demonstrate Neural Tissue Safety Gregory F. Molnar, Dawn Bardot, Kyle J. Myers, Bill Murray, Randall Schiestl , MDIC Computer Modeling & Simulation Project Team

Gregory Molnar Poster MDIC

Publish Date: 
Monday, April 18, 2016 - 10:30am

Abi Muralidharan published

Abi Muralidharan published an article in Experimental Neurology titled
Physiological changes in the pallidum in a progressive model of
Parkinson's disease: Are oscillations enough?
link: http://www.ncbi.nlm.nih.gov/pubmed/26946223

Publish Date: 
Thursday, April 7, 2016 - 4:00pm

NMRC members presenting at the 2016 Minnesota Neuromodulation Symposium

Many individuals in the lab are presenting at the 2016 Minnesota
Neuromodulation Symposium
 

Five posters from the Neuromodulation Research Center will be presented
http://neuromodulation.umn.edu/poster-session/


Luke Johnson is giving a highlight talk:
http://neuromodulation.umn.edu/highlight-talks/

 

 

Publish Date: 
Thursday, April 7, 2016 - 3:45pm